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Pharmacogenomics—What is it?
Pharmacogenomics is an important part of individualized, precision medicine. It is the study of how medications interact with a person’s unique DNA. Knowing ahead of time whether a drug will work for you and if you will have side effects is an invaluable piece of information. It can decrease the trial and error of trying numerous medications before finding one that works, saving valuable time and money. Your age, lifestyle, and surroundings affect your response to medications and so do your genes! Using Pharmacogenomics, healthcare plans can be customized for each individual leading to better outcomes. No more one size fits all approach and only one test is needed for life!
Some common medications that are impacted by genetics below: *List is not all-inclusive
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Depression
Amitriptyline (Elavil®)
Amoxapine (Amoxapine®)
Bupropion (Wellbutrin®)
Citalopram (Celexa®)
Clomipramine (Anafranil®)
Desipramine (Norpramin®)
Desvenlafaxine (Pristiq®)
Escitalopram (Lexapro®)
Imipramine (Tofranil®)
Maprotiline (Ludiomil®)
Nefazodone (Serzone®)
Nortriptyline (Pamelor®)
Paroxetine (Paxil®)
Sertraline (Zoloft®)
Trazodone (Desyrel®)
Venlafaxine (Effexor®)
Vortioxetine (Trintellix®)
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Cadiovascular
Clopidogrel (Plavix®)
Warfarin (Coumadin®)
Atorvastatin (Lipitor®)
Fluvastatin (Lescol®)
Lovastatin (Mevacor®)
Pitavastatin (Livalo®)
Pravastatin (Pravachol®)
Rosuvastatin (Crestor®)
Simvastatin (Zocor®)
Azilsartan (Edarbi®, Edarbyclor®)
Irbesartan (Avapro®)
Losartan (Cozaar®, Hyzaar®)
Metoprolol (Lopressor®)
Nebivolol (Bystolic®)
Flecainide (Tambocor®)
Propafenone (Rythmol®)
Torsemide (Demadex®)
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Pain
Celecoxib (Celebrex®)
Flurbiprofen (Ansaid®)
Ibuprofen (Advil®, Motrin®)
Meloxicam (Mobic®)
Piroxicam (Feldene®)
Benzhydrocodone (Apadaz®)
Codeine (Codeine; Fioricet® with Codeine)
Fentanyl (Actiq®)
Hydrocodone (Vicodin®)
Methadone (Dolophine®)
Morphine (MS Contin®)
Oxycodone (Percocet®, Oxycontin®)
Tramadol (Ultram®)
Carisoprodol (Soma®)
Tizanidine (Zanaflex®)
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Bipolar
Aripiprazole (Abilify®, Aristada®)
Brexpiprazole (Rexulti®)
Chlorpromazine (Thorazine®)
Clozapine (Clozaril®)
Doxepin (Silenor®)
Escitalopram (Lexapro®)
Fluoxetine (Prozac®)
Fluvoxamine (Luvox®)
Haloperidol (Haldol®)
Iloperidone (Fanapt®)
Olanzapine (Zyprexa®)
Paliperidone (Invega®)
Risperidone (Risperdal®)
Thioridazine (Mellaril®)
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Cancer
Azathioprine (Imuran®)
Capecitabine (Xeloda®)
Erdafitinib (Balversa®)
Fluorouracil (Efudex®)
Gefitinib (Iressa®)
Mercaptopurine (Purinethol®)
Methotrexate (Trexall®)
Tamoxifen (Nolvadex®)
Thioguanine (Tabloid®)
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Epilepsy
Carbamazepine (Tegretol®)
Clobazam (Onfi®)
Fosphenytoin (Cerebyx®)
Lamotrigine (Lamictal®)
Oxcarbazepine (Trileptal®)
Phenobarbital (Luminal®)
Phenytoin (Dilantin®)
Primidone (Mysoline®)
Zonisamide (Zonegran®)
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ADHD
Amphetamine (Adderall®)
Atomoxetine (Straterra®)
Dexmethylphenidate (Focalin®)
Dextroamphetamine (Dexedrine®)
Lisdexamfetamine (Vyvanse®)
Methylphenidate (Ritalin®)
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Additionally
Donepezil (Aricept®)
Galantamine (Razadyne®)
Dextromethorphan/Quinidine (Nuedexta®)
Allopurinol (Zyloprim®)
Diazepam (Valium)